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Prevalence and predictors of immunologic failure among HIV patients on HAART in southern Ethiopia

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dc.contributor.advisor Hattingh, Susan
dc.contributor.author Kesetebirhan Delele Yirdaw
dc.date.accessioned 2015-08-20T08:42:02Z
dc.date.available 2015-08-20T08:42:02Z
dc.date.issued 2014-11
dc.date.submitted 2015-08-20
dc.identifier.citation Kesetebirhan Delele Yirdaw (2014) Prevalence and predictors of immunologic failure among HIV patients on HAART in southern Ethiopia, University of South Africa, Pretoria, <http://hdl.handle.net/10500/18970> en
dc.identifier.uri http://hdl.handle.net/10500/18970
dc.description.abstract Immunologic monitoring is part of the standard care for patients on antiretroviral treatment. Yet, little is known about the routine implementation of immunologic monitoring in Ethiopia. This study assessed the pattern of immunologic monitoring, immunologic response, level of immunologic treatment failure and factors related to it among patients on antiretroviral therapy in selected hospitals in southern Ethiopia. A retrospective longitudinal analytic study was conducted using documents of patients started on antiretroviral therapy. A total of 1,321 documents of patients reviewed revealed timely immunologic monitoring were inadequate. Despite overall adequate immunologic response, the prevalence of immunologic failure was 11.5% (n=147). Having WHO Stage III/IV of the disease and a higher CD4 (cluster differentiation 4) cell count at baseline were identified as risks for immunologic failure. These findings highlight the magnitude of the problem of immunologic failure. Prioritizing monitoring for high risk patients may help in effective utilisation of meager resources en
dc.format.extent 1 online resource (xiii, 144 leaves) : tables, graphs, maps en
dc.language.iso en en
dc.subject Human Immunodeficiency Virus en
dc.subject CD4 cell en
dc.subject Highly active antiretroviral therapy (HAART) en
dc.subject Adherence en
dc.subject Immunologic treatment failure en
dc.subject Antiretroviral treatment failure en
dc.subject Prevalence en
dc.subject Patient en
dc.subject Predict en
dc.subject.ddc 615.79240963
dc.subject.lcsh Highly active antiretroviral therapy en
dc.subject.lcsh HIV infections -- Ethiopia -- Immunological aspects en
dc.title Prevalence and predictors of immunologic failure among HIV patients on HAART in southern Ethiopia en
dc.type Dissertation en
dc.description.department Health Studies en
dc.description.degree M. A. (Public Health) en


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