Nitric oxide triggered dephosphorylation reactions

Enemchukwu, Emeka Martin

dc.contributor.advisor	Tafesse, F.
dc.contributor.author	Enemchukwu, Emeka Martin
dc.date.accessioned	2009-10-01T13:25:13Z
dc.date.available	2009-10-01T13:25:13Z
dc.date.issued	2009-01
dc.identifier.citation	Enemchukwu, Emeka Martin (2009) Nitric oxide triggered dephosphorylation reactions, University of South Africa, Pretoria, <http://hdl.handle.net/10500/2637>	en
dc.identifier.uri	http://hdl.handle.net/10500/2637
dc.description.abstract	The synergistic effect of nitric oxide toward dephosphorylation reactions involving phosphate esters was the subject of investigation in this research. Sodium nitroprusside under UV irradiations at 254nm, 365nm and white light was utilized as nitric oxide donor in solutions. The effects of cobalt trimethylenediamine and nitroprusside towards dephosphorylation of nitrophenylphosphate and pyrophosphate which were modeled as organophosphate ester substrates were also investigated. The activated substrate models showed more rate enhancement than the unactivated models in all cases. The direct interaction of nitric oxide with the phosphorus centre is presumed to be the reason for enhanced hydrolysis. This study demonstrates the possible role of nitric oxide in decontamination reactions of poorly biodegradable phosphate esters in the biosphere.	en
dc.format.extent	1 online resource (xiv, 78 leaves : ill.)
dc.language.iso	en	en
dc.subject	Nitric oxide	en
dc.subject	Nitrophenylphosphate	en
dc.subject	Sodium nitroprusside	en
dc.subject	Dephosphorylation	en
dc.subject	Phototransformation
dc.subject	Decontamination
dc.subject	Inorganic phosphate
dc.subject	Inorganic pyrophosphate
dc.subject	Nitrophenolate ion
dc.subject	Trimethylenediamine
dc.subject	Organophosphate esters
dc.subject	Ultra violet radiation
dc.subject.ddc	541.39
dc.subject.lcsh	Nitric oxide
dc.subject.lcsh	Phosphate esters
dc.subject.lcsh	Ultraviolet radiation
dc.title	Nitric oxide triggered dephosphorylation reactions	en
dc.type	Dissertation	en
dc.description.department	Chemistry
dc.description.degree	M. Sc. (Chemistry)