Browsing Work in progress by Subject "Glycyrrhetinic acid; Glycyrrhizinate; Perfused intestine; Perfused liver; Pharmacokinetics; Rat diammonium glycyrrhizinate; glycyrrhetinic acid; Glycyrrhiza extract; unclassified drug; animal tissue; area under the curve; article; controlled study; drug absorption; drug bioavailability; drug disposition; drug formulation; Glycyrrhiza; high performance liquid chromatography; in vivo study; intestine flora; male; nonhuman; organ perfusion; rat; Animals; Glycyrrhetinic Acid; Glycyrrhizic Acid; Intestinal Absorption; Intestine, Small; Liver; Male; Perfusion; Rats; Rats, Sprague-Dawley; Rattus"

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The disposition of diammonium glycyrrhizinate and glycyrrhetinic acid in the isolated perfused rat intestine and liver

Yang J.; Zhou L.; Wang J.; Wang C.; Davey A.K. (2008)

The major component of liquorice root extract, glycyrrhizinate (GZ), has been formulated as an injection for the treatment of hepatitis. If given orally, GZ has poor bioavailability and is catalysed to glycyrrhetinic acid ...

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