Institutional Repository

Tautomeric 2-arylquinolin-4(1H)-one derivatives- spectroscopic, X-ray and quantum chemical structural studies

UnisaIR/Manakin Repository

Show simple item record

dc.contributor.author Mphahlele M.J. en
dc.contributor.author El-Nahas A.M. en
dc.date.accessioned 2012-11-01T16:31:36Z
dc.date.available 2012-11-01T16:31:36Z
dc.date.issued 2004 en
dc.identifier.citation Journal of Molecular Structure en
dc.identifier.citation 688 en
dc.identifier.citation 03-Jan en
dc.identifier.issn 222860 en
dc.identifier.other 10.1016/j.molstruc.2003.10.003 en
dc.identifier.uri http://hdl.handle.net/10500/7437
dc.description.abstract A convenient method for the synthesis of 2-aryl-1-methylquinolin-4(1H) -ones is described. Spectroscopic and X-ray crystallographic techniques as well as quantum chemical calculations have been used to probe the structure of potentially tautomeric 2-arylquinolin-4(1H)-ones in solution phase, gas phase and solid state. The exclusive NH-4-oxo nature of the title compounds in solution phase (NMR) and solid state (IR and X-ray) is also corroborated by comparison of their spectroscopic data with those of the corresponding 2-aryl-1-methylquinolin-4(1H)-one and 2-aryl-4-methoxyquinoline derivatives. Results from mass spectrometric analysis confirm the coexistence of the 4-quinolinone and 4-hydroxyquinoline isomers in the gas phase and this is supported by quantum chemical computations. © 2003 Elsevier B.V. All rights reserved. en
dc.language.iso en en
dc.subject 2-Arylquinolin-4(1H)-ones; Solution phase, solid state and gas phase studies quinoline derivative; article; drug structure; drug synthesis; gas; infrared spectroscopy; mass spectrometry; mathematical computing; nuclear magnetic resonance; quantum chemistry; solid state; X ray crystallography en
dc.title Tautomeric 2-arylquinolin-4(1H)-one derivatives- spectroscopic, X-ray and quantum chemical structural studies en
dc.type Article en


Files in this item

Files Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record

Search UnisaIR


Browse

My Account

Statistics