Browsing Theses and Dissertations (Life and Consumer Sciences) by Subject "Shikimate kinase"

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Mycobacterium tuberculosis kinases as potential drug targets: production of recombinant kinases in E. coli for functional characterization and enzyme inhibition screening against the medicinal plant Pelargonium sidoides

Lukman, Vishani (2015-01)

Tuberculosis (TB) is an infectious and fatal disease that ranks as the second leading killer worldwide. It is caused by Mycobacterium tuberculosis (Mtb) which is an obligate intracellular parasite that colonizes the alveolar ...
Regulation of kinases by synthetic imidazoles, nucleotides and their deuterated analogues

Nkosi, Thokozani Clement (2015-02)

Deuteration is the replacement of a hydrogen atom by deuterium atom in a molecule. The replacement begins at the most acidic hydrogen in the molecule. In ATP, the deshielded hydrogen is C8-H which is the first replaced ...

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