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A comparison of the effectiveness of protease inhibitor-based highly active anti-retroviral treatment regiments in Trinidad and Tobago

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dc.contributor.advisor Ehlers, V. J.
dc.contributor.author Ziregbe, Elohor
dc.date.accessioned 2014-10-21T12:30:43Z
dc.date.available 2014-10-21T12:30:43Z
dc.date.issued 2013-11
dc.date.submitted 2014-10-21
dc.identifier.citation Ziregbe, Elohor (2013) A comparison of the effectiveness of protease inhibitor-based highly active anti-retroviral treatment regiments in Trinidad and Tobago, University of South Africa, Pretoria, <http://hdl.handle.net/10500/14199> en
dc.identifier.uri http://hdl.handle.net/10500/14199
dc.description.abstract Few studies have assessed the optimum second line highly active anti-retroviral therapy (HAART) regimen in patients who had failed on the first-line HAART in resource-limited settings. This study aimed to compare the Protease inhibitor (PI)-based second line HAART regimens used in one clinic in Trinidad by comparing immunological, virological and clinical outcomes of patients on the different second line HAART regimens. The records of 35 treatment-experienced patients, over 21years of age and on PI-based regimens for at least six months, were analysed using SPSS version 20. The regimen containing TDF/FTC/AZT/LPV/r proved to produce superior outcomes compared to the other second line regimens. Due the small number of usable patients’ records, the findings cannot be generalised but indicate directions for future studies attempting to compare the treatment outcomes of different second line HAART regimens en
dc.format.extent 1 online resource (xiv, 90 leaves)
dc.language.iso en en
dc.subject Highly active anti-retroviral treatment (HAART) en
dc.subject 1st HAART regimens en
dc.subject 2nd line HAART regiments en
dc.subject Resistance to anti-retroviral drugs en
dc.subject Treatment adherence en
dc.subject.ddc 615.79240972983
dc.subject.lcsh Protease inhibators -- Trinidad
dc.subject.lcsh Highly active antiretroviral therapy
dc.subject.lcsh HIV infections -- Treatment -- Trinidad
dc.subject.lcsh AIDS (Disease) -- Treatment -- Trinidad
dc.title A comparison of the effectiveness of protease inhibitor-based highly active anti-retroviral treatment regiments in Trinidad and Tobago en
dc.type Dissertation en
dc.description.department Health Studies en
dc.description.degree M. A. (Public Health)


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