Rosuvastatin is transferred into human breast milk: A case report.

Abstract

Controversy exists on whether lactating women with familial hypercholesterolemia should resume statin treatment. This is partly due to the unavailability of data in humans regarding the transfer of statins into breast milk. Statin manufacturers advise against statin use for nursing mothers, referring to a study on rats indicating the transfer of atorvastatin via breast milk.1 It is generally accepted that statin levels of animal breast milk may not accurately reflect human breast milk levels. To our best knowledge no published data is available on the transfer of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors via breast milk in humans.